PT - JOURNAL ARTICLE AU - Saskia M. Willers AU - Charlotta Eriksson AU - Lars Gidhagen AU - Mats E. Nilsson AU - Göran Pershagen AU - Tom Bellander TI - Fine and coarse particulate air pollution in relation to respiratory health in Sweden AID - 10.1183/09031936.00088212 DP - 2013 Oct 01 TA - European Respiratory Journal PG - 924--934 VI - 42 IP - 4 4099 - http://erj.ersjournals.com/content/42/4/924.short 4100 - http://erj.ersjournals.com/content/42/4/924.full SO - Eur Respir J2013 Oct 01; 42 AB - Health effects have repeatedly been associated with residential levels of air pollution. However, it is difficult to disentangle effects of long-term exposure to locally generated and long-range transported pollutants, as well as to exhaust emissions and wear particles from road traffic. We aimed to investigate effects of exposure to particulate matter fractions on respiratory health in the Swedish adult population, using an integrated assessment of sources at different geographical scales.The study was based on a nationwide environmental health survey performed in 2007, including 25 851 adults aged 18–80 years. Individual exposure to particulate matter at residential addresses was estimated by dispersion modelling of regional, urban and local sources. Associations between different size fractions or source categories and respiratory outcomes were analysed using multiple logistic regression, adjusting for individual and contextual confounding.Exposure to locally generated wear particles showed associations for blocked nose or hay fever, chest tightness or cough, and restricted activity days with odds ratios of 1.5–2 per 10-μg·m−3 increase. Associations were also seen for locally generated combustion particles, which disappeared following adjustment for exposure to wear particles.In conclusion, our data indicate that long-term exposure to locally generated road wear particles increases the risk of respiratory symptoms in adults.Long-term exposure to locally generated road wear particles increases the risk of respiratory symptoms in adults http://ow.ly/nutsB