RT Journal Article
SR Electronic
T1 Thoracoscore fails to predict complications following elective lung resection
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 1496
OP 1501
DO 10.1183/09031936.00218111
VO 40
IS 6
A1 Amy Bradley
A1 Andrea Marshall
A1 Mahmoud Abdelaziz
A1 Khalid Hussain
A1 Paula Agostini
A1 Ehab Bishay
A1 Maninder Kalkat
A1 Richard Steyn
A1 Pala Rajesh
A1 Janet Dunn
A1 Babu Naidu
YR 2012
UL http://erj.ersjournals.com/content/40/6/1496.abstract
AB The Thoracoscore mortality risk model has been incorporated into the British Thoracic Society guidelines on the radical management of patients with lung cancer. The discriminative and predictive ability to predict mortality and post-operative pulmonary complications (PPCs) in this group of patients is uncertain. A prospective observational study was carried out on all patients following lung resection via thoracotomy in a regional thoracic centre over 42 months. 128 out of 703 subjects developed a PPC. 16 (2%) patients died in hospital. In a logistic regression analysis the Thoracoscore was not a significant predictor of mortality (OR 1.07, 95% CI 0.99–1.17; p=0.11) but was a significant predictor of PPCs (OR 1.08, 95% CI 1.03–1.13; p=0.002). However, the area under the receiver operator characteristic curve for the Thoracoscore was 0.68 (95% CI 0.56–0.80) for predicting mortality and 0.64 (95% CI 0.59–0.69) for PPCs, indicating limited discriminative ability. In a logistic regression analysis, another risk model, the European Society Objective Score, was predictive of mortality (OR 1.43, 95% CI 1.11–1.83; p=0.006) and PPCs (OR 1.48, 95% CI 1.30–1.68; p<0.0001). Therefore, Thoracoscore may have poor discriminative and predictive ability for mortality and PPCs following elective lung resection.