RT Journal Article
SR Electronic
T1 Anti-reflux surgery in lung transplant recipients: outcomes and effects on quality of life
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 691
OP 697
DO 10.1183/09031936.00061811
VO 39
IS 3
A1 A.G.N. Robertson
A1 A. Krishnan
A1 C. Ward
A1 J.P. Pearson
A1 T. Small
A1 P.A. Corris
A1 J.H. Dark
A1 D. Karat
A1 J. Shenfine
A1 S.M. Griffin
YR 2012
UL http://erj.ersjournals.com/content/39/3/691.abstract
AB Fundoplication may improve survival after lung transplantation. Little is known about the effects of fundoplication on quality of life in these patients. The aim of this study was to assess the safety of fundoplication in lung transplant recipients and its effects on quality of life. Between June 1, 2008 and December 31, 2010, a prospective study of lung transplant recipients undergoing fundoplication was undertaken. Quality of life was assessed before and after surgery. Body mass index (BMI) and pulmonary function were followed up. 16 patients, mean±sd age 38±11.9 yrs, underwent laparoscopic Nissen fundoplication. There was no peri-operative mortality or major complications. Mean±sd hospital stay was 2.6±0.9 days. 15 out of 16 patients were satisfied with the results of surgery post fundoplication. There was a significant improvement in reflux symptom index and DeMeester questionnaires and gastrointestinal quality of life index scores at 6 months. Mean BMI decreased significantly after fundoplication (p=0.01). Patients operated on for deteriorating lung function had a statistically significant decrease in the rate of lung function decline after fundoplication (p=0.008). Laparoscopic fundoplication is safe in selected lung transplant recipients. Patient benefit is suggested by improved symptoms and satisfaction. This procedure is acceptable, improves quality of life and may reduce deterioration of lung function.