TY - JOUR T1 - Self-reported sleep apnoea and mortality in patients from the Swedish Obese Subjects study JF - European Respiratory Journal JO - Eur Respir J SP - 1349 LP - 1354 DO - 10.1183/09031936.00022111 VL - 38 IS - 6 AU - N.S. Marshall AU - L. Delling AU - R.R. Grunstein AU - M. Peltonen AU - C.D. Sjöström AU - K. Karason AU - L.M.S. Carlsson AU - J. Hedner AU - K. Stenlöf AU - L. Sjöström Y1 - 2011/12/01 UR - http://erj.ersjournals.com/content/38/6/1349.abstract N2 - Sleep apnoea is associated with increased mortality in sleep clinic and community population groups. It is unclear whether a clinical report of sleep apnoea results in additional mortality risk in patients with severe obesity. The Swedish Obese Subjects (SOS) study is a nonrandomised controlled trial of bariatric surgery versus conventional treatment for the treatment of severe obesity and its complications (mean±sd body mass index 41±5 kg·m−2). The presence or absence of sleep apnoea (witnessed pauses in breathing) was determined by self-reporting at baseline in 3,953 patients who were observed for 54,236 person-yrs (mean 13.5 maximum 21.0 yrs). Sleep apnoea was reported by 934 (23.6%) patients at baseline and was a significant univariate predictor of mortality (hazard ratio (95% CI) 1.74 (1.40–2.18)). In a range of multivariate models of mortality risk, controlling for ≤16 other potential confounders and established mortality risk factors, sleep apnoea remained a significant prognostic factor (fully adjusted model 1.29 (1.01–1.65)). Self-reported sleep apnoea is an independent prognostic marker of all-cause mortality in obese patients. ER -