RT Journal Article
SR Electronic
T1 Acute respiratory distress syndrome due to methicillin-resistant Staphylococcus aureus sepsis in hyper-IgE syndrome
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 386
OP 388
DO 10.1183/09031936.96.09020386
VO 9
IS 2
A1 Sato, E
A1 Yamamoto, H
A1 Honda, T
A1 Koyama, S
A1 Kubo, K
A1 Sediguchi, M
YR 1996
UL http://erj.ersjournals.com/content/9/2/386.abstract
AB We report the case of a 34 year old woman with acute respiratory distress syndrome (ARDS) and disseminated intravascular coagulation (DIC) due to methicillin-resistant Staphylococcus aureus (MRSA) sepsis with hyperimmunoglobulin E syndrome (HIES). Although chemotactic activity of neutrophils was impaired in this patient, neutrophils accumulated in the lungs as assessed by bronchoalveolar lavage fluid (BALF) counts. In addition to antibiotics and oxygen therapy, the administration of recombinant human granulocyte colony-stimulating factor (rhG-CSF) resulted in a remarkable recovery.