PT - JOURNAL ARTICLE AU - E Sato AU - H Yamamoto AU - T Honda AU - S Koyama AU - K Kubo AU - M Sediguchi TI - Acute respiratory distress syndrome due to methicillin-resistant Staphylococcus aureus sepsis in hyper-IgE syndrome AID - 10.1183/09031936.96.09020386 DP - 1996 Feb 01 TA - European Respiratory Journal PG - 386--388 VI - 9 IP - 2 4099 - http://erj.ersjournals.com/content/9/2/386.short 4100 - http://erj.ersjournals.com/content/9/2/386.full SO - Eur Respir J1996 Feb 01; 9 AB - We report the case of a 34 year old woman with acute respiratory distress syndrome (ARDS) and disseminated intravascular coagulation (DIC) due to methicillin-resistant Staphylococcus aureus (MRSA) sepsis with hyperimmunoglobulin E syndrome (HIES). Although chemotactic activity of neutrophils was impaired in this patient, neutrophils accumulated in the lungs as assessed by bronchoalveolar lavage fluid (BALF) counts. In addition to antibiotics and oxygen therapy, the administration of recombinant human granulocyte colony-stimulating factor (rhG-CSF) resulted in a remarkable recovery.