TY - JOUR T1 - Systemic sarcoidosis initially presenting as an orbital tumour JF - European Respiratory Journal JO - Eur Respir J SP - 474 LP - 476 DO - 10.1183/09031936.95.08030474 VL - 8 IS - 3 AU - M Faller AU - A Purohit AU - N Kennel AU - F de Blay AU - J Sahel AU - G Pauli Y1 - 1995/03/01 UR - http://erj.ersjournals.com/content/8/3/474.abstract N2 - A 73 year old woman presented with redness, itching and painless proptosis of the left eye. Clinical examination and computed tomographic (CT) scan of the orbit revealed a postero-ocular mass, the biopsy of which showed a noncaseating, giant cellular, epithelioid granuloma compatible with sarcoidosis. The patient had no respiratory complaints, but the thoracic CT scan showed multiple bilateral hilar and mediastinal adenopathies. Gallium scan showed increased uptake in both hilar regions, in the left orbit and in the right parotid gland. Multiple bronchial biopsies revealed sarcoid granulomas, with a bronchoalveolar lavage (BAL) cytological pattern of active sarcoidosis. The evolution was favourable with prednisolone given at a dose of 0.5 mg.kg-1 daily. It is suggested that in an unusual presentation of sarcoidosis, a thorough search should be made for localization at other sites, lungs in particular, even in the absence of respiratory complaints. ER -