PT  - JOURNAL ARTICLE
AU  - Gasche, Y
AU  - Romand, JA
AU  - Pretre, R
AU  - Suter, PM
TI  - IVOX in ARDS: respiratory effects and serious complications
AID  - 10.1183/09031936.94.07040821
DP  - 1994 Apr 01
TA  - European Respiratory Journal
PG  - 821--823
VI  - 7
IP  - 4
4099  - http://erj.ersjournals.com/content/7/4/821.short
4100  - http://erj.ersjournals.com/content/7/4/821.full
SO  - Eur Respir J1994 Apr 01; 7
AB  - We describe the beneficial effects of an intravenous oxygenator (IVOX) on ventilatory pressure requirement, and also several severe complications related to its use in a young trauma victim developing severe acute respiratory distress syndrome (ARDS). In this patient, adequate systemic oxygenation could not be maintained despite the use of fractional inspired oxygen of 1.0, high level positive end-expiratory pressure (PEEP), and nitric oxide inhalation (30 ppm). The introduction of an intravenous oxygenator improved arterial oxygenation and CO2 elimination, allowing a decrease in minute ventilation and airway pressure. However, hepatic cytolysis, acute renal dysfunction and iliac vein thrombosis developed concomitantly, in spite of full anticoagulation with heparin. These complications resolved rapidly after removal of the IVOX device and the patient made a good recovery.