TY - JOUR T1 - The effect of nanoparticles on airway allergy in mice JF - European Respiratory Journal JO - Eur Respir J SP - 1300 LP - 1301 DO - 10.1183/09031936.00027211 VL - 37 IS - 5 AU - K-I. Inoue AU - H. Takano Y1 - 2011/05/01 UR - http://erj.ersjournals.com/content/37/5/1300.abstract N2 - To the Editors:We read with great interest a recent experimental (in vivo) study by Hussain et al. 1 and would like to comment on that article. First of all, we were very interested in the overall results that a single airway exposure to relatively low dose (16 μg·mouse−1) of nanoparticles facilitates allergic airway inflammation. We have previously examined several types of nanoparticles/nanomaterials on ovalbumin-induced airway inflammation 2–5. However, the doses were higher (25–100 μg·mouse−1 administered weekly a total of seven times) and provoked a more moderate increase in the number of inflammatory leukocytes into bronchoalveolar spaces in the absence of allergen than that in the present study by Hussain et al. … ER -