RT Journal Article SR Electronic T1 Isolated intrathoracic tuberculous lymphadenopathy JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 758 OP 760 DO 10.1183/09031936.93.04060758 VO 4 IS 6 A1 P Van den Brande A1 J Vijgen A1 M Demedts YR 1991 UL http://erj.ersjournals.com/content/4/6/758.abstract AB We report an 82 yr old man with isolated intrathoracic lymphadenopathy of tuberculous origin, which is an extremely uncommon presentation of tuberculosis especially in elderly Caucasian patients. The diagnosis was suggested by the computerized tomographic (CT)-scan showing central hypodense areas after contrast, and was subsequently proved by mediastinoscopic biopsy with histological and microbiological analysis. The atypical presentation of tuberculosis together with a negative two-step 5 international units of purified protein derivative (IU-PPD) tuberculin skin test and a frequent contact with a cavernous index case points towards a primary infection in this patient.