RT Journal Article SR Electronic T1 Therapeutic compliance in asthma; its magnitude and implications JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 122 OP 124 DO 10.1183/09031936.93.05010122 VO 5 IS 1 A1 GM Cochrane YR 1992 UL http://erj.ersjournals.com/content/5/1/122.1.abstract AB Failure to heed medical advice is common, but the precise extent is poorly understood and barely investigated. Factors leading to poor compliance are not known but claims of lack of education are frequently mentioned. However these have yet to be scientifically substantiated. The frequency of medication and social and economic factors, allied to poor communication, are probably involved but do not account for it entirely as non-compliance may vary between 20-80% of patient populations. Asthma mortality is not decreasing despite effective medication and increasingly there are worries that poor compliance may be a significant factor.