TY - JOUR T1 - Do β<sub>2</sub>-agonists inhibit capsaicin-induced cough? JF - European Respiratory Journal JO - Eur Respir J SP - 459 LP - 460 DO - 10.1183/09031936.00057410 VL - 36 IS - 2 AU - N. Ohkura AU - M. Fujimura AU - A. Tokuda AU - N. Katayama Y1 - 2010/08/01 UR - http://erj.ersjournals.com/content/36/2/459.2.abstract N2 - To the Editors:We read with great interest the paper by Freund-Michel et al. 1 in a recent issue of the European Respiratory Journal, because the results are inconsistent with the medical common sense that β2-agonists do not have common antitussive property.The authors showed that a β2-agonist, terbutaline (0–3 mg·kg−1), dose-dependently inhibited 10−4 M capsaicin-induced cough in conscious guinea pigs. Terbutaline also blocked sensory nerve activation. They concluded that β2-agonists are antitussive and directly inhibit sensory nerve activation.We have shown that the number of 10−4 M capsaicin-induced coughs was extremely increased 24 h after … ER -