PT  - JOURNAL ARTICLE
AU  - Hjellvik, V.
AU  - Tverdal, A.
AU  - Furu, K.
TI  - Body mass index as predictor for asthma: a cohort study of 118,723 males and females
AID  - 10.1183/09031936.00192408
DP  - 2010 Jun 01
TA  - European Respiratory Journal
PG  - 1235--1242
VI  - 35
IP  - 6
4099  - http://erj.ersjournals.com/content/35/6/1235.short
4100  - http://erj.ersjournals.com/content/35/6/1235.full
SO  - Eur Respir J2010 Jun 01; 35
AB  - The objective of the present study was to quantify the relationship between body mass index (BMI; in kilogrammes per metre squared) and asthma in middle-aged males and females, and to evaluate change in BMI as a risk factor for asthma. Asthma incidence was estimated from data on redeemed prescriptions of anti-asthmatic drugs during the period 2004–2007, retrieved from the nationwide Norwegian Prescription Database. BMI was measured during health surveys in 1994–1999 in >100,000 individuals born during 1952–1959. Change in BMI was based on self-report. Relative risks were estimated using Poisson regression. The relative risk associated with a 3-unit increase in BMI ranged from 1.14 (95% confidence interval 1.10–1.18) in current smokers to 1.27 (1.22–1.32) in never-smokers after adjusting for confounders. The relative risk associated with a 3-unit increase in BMI was 1.21 (1.16–1.26) after adjusting for confounders, including sex, smoking and BMI. Asthma incidence, as measured by anti-asthmatic drug use, was positively related to both BMI and change in BMI. For BMI, the association was stronger for never-smokers than for ex-smokers and current smokers.