TY - JOUR T1 - Rituximab therapy in autoimmune pulmonary alveolar proteinosis JF - European Respiratory Journal JO - Eur Respir J SP - 1503 LP - 1506 DO - 10.1183/09031936.00160908 VL - 33 IS - 6 AU - R. Borie AU - M-P. Debray AU - C. Laine AU - M. Aubier AU - B. Crestani Y1 - 2009/06/01 UR - http://erj.ersjournals.com/content/33/6/1503.abstract N2 - Idiopathic pulmonary alveolar proteinosis is presumed to be an autoimmune disorder that may lead to pulmonary insufficiency. However, steroids do not appear to be effective and the standard of therapy is whole-lung lavage. We report the first case of successful therapy with rituximab, which addresses the pathogenic mechanism of pulmonary alveolar proteinosis. ER -