PT  - JOURNAL ARTICLE
AU  - J Gluskowski
AU  - I Hawrylkiewicz
AU  - D Zych
AU  - J Zielinski
TI  - Effects of corticosteroid treatment on pulmonary haemodynamics in patients with sarcoidosis
AID  - 10.1183/09031936.93.03040403
DP  - 1990 Apr 01
TA  - European Respiratory Journal
PG  - 403--407
VI  - 3
IP  - 4
4099  - http://erj.ersjournals.com/content/3/4/403.short
4100  - http://erj.ersjournals.com/content/3/4/403.full
SO  - Eur Respir J1990 Apr 01; 3
AB  - Effects of 12 months steroid treatment on pulmonary haemodynamics in 24 patients with pulmonary sarcoidosis, stage II and III, were investigated. All patients had a chest radiograph, lung function tests, and pulmonary haemodynamics (measured at rest and during submaximal exercise) prior to the treatment. Resting pulmonary hypertension was found in 3 patients. In 18 an abnormal increase in pulmonary arterial mean pressure (PAP) on exercise was observed. All investigations were repeated after a year of treatment. In almost all patients (22) a regression of radiological changes in the lungs and improvement of pulmonary function were observed. The changes in pulmonary circulation were less uniform. In only half of the patients studied was regression of the disease seen on chest X-ray and improvement in lung function accompanied by improvement in pulmonary haemodynamics.