RT Journal Article SR Electronic T1 Mycobacterium avium complex disease: prognostic implication of high-resolution computed tomography findings JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 147 OP 152 DO 10.1183/09031936.00074207 VO 32 IS 1 A1 S. Kuroishi A1 Y. Nakamura A1 H. Hayakawa A1 M. Shirai A1 Y. Nakano A1 K. Yasuda A1 T. Suda A1 H. Nakamura A1 K. Chida YR 2008 UL http://erj.ersjournals.com/content/32/1/147.abstract AB To evaluate the prognostic implications of computed tomography (CT) findings in assessing responses to treatment in Mycobacterium avium complex (MAC) pulmonary disease without underlying lung disease, high-resolution (HR)CT findings were correlated based on the results of sputum conversion after anti-MAC therapy. A total of 59 patients underwent HRCT before treatment and the therapeutic efficacy was evaluated by the results of sputum conversion. Atelectasis, cavities and pleural thickening on HRCT were significantly more frequent and extensive among patients in the sputum nonconverted group than among those in the converted group. Furthermore, bronchiectasis was also significantly more extensive among patients in the nonconverted group, even though there was no significant difference in frequency between these two groups. These results suggest that high-resolution computed tomography findings are good predictors of response to treatment in Mycobacterium avium complex pulmonary disease.