RT Journal Article
SR Electronic
T1 Imprint cytology improves accuracy of computed tomography-guided percutaneous transthoracic needle biopsy
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 54
OP 61
DO 10.1183/09031936.00038907
VO 31
IS 1
A1 Y-C. Chang
A1 C-J. Yu
A1 W-J. Lee
A1 S-H. Kuo
A1 C-H. Hsiao
A1 I-S. Jan
A1 F-C. Hu
A1 H-M. Liu
A1 W-K. Chan
A1 P-C. Yang
YR 2008
UL http://erj.ersjournals.com/content/31/1/54.abstract
AB The aim of the present study was to investigate whether imprint cytology can improve the diagnostic accuracy of computed tomography-guided transthoracic core biopsy. Between October 1997 and June 2004, thoracic lesions in 622 patients underwent biopsy using 19-gauge coaxial guiding needles and 20-gauge biopsy needles under computed tomography guidance. Touch imprint cytology and histopathology were performed for all biopsy specimens. Of these lesions, 431 (74.1%) were diagnosed as malignant, 151 (25.9%) as benign and 40 (6%) as nondiagnostic. Imprint cytology plus histology shows an improved diagnostic accuracy of 96.4% compared with that of imprint cytology alone (92.3%) or histopathology alone (93.0%). Procedure-related complications requiring further treatment occurred in eight (1.4%) patients. In conclusion, imprint cytology combined with histopathology can improve the diagnostic accuracy of computed tomography-guided transthoracic needle biopsy.