RT Journal Article SR Electronic T1 First months of employment and new onset of rhinitis in adolescents JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 549 OP 555 DO 10.1183/09031936.00149206 VO 30 IS 3 A1 E. Riu A1 H. Dressel A1 D. Windstetter A1 G. Weinmayr A1 S. Weiland A1 C. Vogelberg A1 W. Leupold A1 E. von Mutius A1 D. Nowak A1 K. Radon YR 2007 UL http://erj.ersjournals.com/content/30/3/549.abstract AB The aim of the present study was to investigate the incidence of rhinitis in adolescents, taking into account the duration and type of employment in holiday and vocational jobs, and to study latency until development of symptoms. Participants of the International Study of Asthma and Allergies in Childhood (ISAAC)-II study in Munich and Dresden (Germany), who were enrolled in 1995, were re-contacted by a postal questionnaire in 2002 (aged 16–18 yrs). The questionnaire focused on allergic rhinitis, type and duration of all jobs, and potential confounders. All jobs held for ≥8 h·week−1 and ≥1 month were coded and occupational exposure was assigned by a job-exposure matrix. Out of the 3,785 participants, 964 reported an employment history. The median (25th–75th percentile) duration of employment was 10 (1–16) months. After adjusting for potential confounders, those working in high-risk occupations (odds ratio (OR) 1.4, 95% confidence interval (CI) 1.0–2.1) had an increased risk for new onset of rhinitis, especially those exposed to low molecular weight agents (OR 1.8, 95% CI 1.1–2.8). The incidence of rhinitis was highest among those currently employed in a high-risk job for <10 months. Teenagers who start working in high-risk occupations have a higher incidence of rhinitis compared with those not working. This increased risk might occur early on during employment.