RT Journal Article
SR Electronic
T1 Estimation of the bronchodilatory effect of deep inhalation after a free run in children
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 89
OP 95
DO 10.1183/09031936.06.00114705
VO 28
IS 1
A1 C. Schweitzer
A1 L. T. T. Vu
A1 Y. T. Nguyen
A1 C. Choné
A1 B. Demoulin
A1 F. Marchal
YR 2006
UL http://erj.ersjournals.com/content/28/1/89.abstract
AB The bronchomotor effects of a deep inhalation (DI) may provide relevant information about the mechanisms of exercise-induced airway obstruction in children and may be assessed by respiratory conductance (Grs) measured using the forced oscillation technique. The aims of the present study were to assess the effect of DI on Grs after exercise in relationship to the lung function response to exercise. Grs at 12 Hz using a head generator and spirometric data were measured in 62 children suspected of asthma before and 5 min after a 6-min free run. After exercise, Grs was significantly increased by DI in 38 subjects, who also showed larger Grs and forced expiratory volume in one second (FEV1)/forced vital capacity (FVC) responses to exercise than the 24 nonresponders. Stepwise regression indicated significant correlation between the response of Grs to DI and both Grs and FEV1/FVC responses to exercise. The data are consistent with exercise-induced bronchoconstriction being reversed by deep inhalation.