PT - JOURNAL ARTICLE AU - L. C. Dort AU - E. Hadjuk AU - J. E. Remmers TI - Mandibular advancement and obstructive sleep apnoea: a method for determining effective mandibular protrusion AID - 10.1183/09031936.06.00077804 DP - 2006 May 01 TA - European Respiratory Journal PG - 1003--1009 VI - 27 IP - 5 4099 - http://erj.ersjournals.com/content/27/5/1003.short 4100 - http://erj.ersjournals.com/content/27/5/1003.full SO - Eur Respir J2006 May 01; 27 AB - The objectives of the study were to test the hypotheses that it is possible, during routine polysomnography (PSG), to prospectively identify favourable candidates for mandibular repositioning appliance (MRA) therapy in the treatment of obstructive sleep apnoea (OSA) and to accurately estimate an optimal protrusive distance at which to fabricate the MRA. A series of subjects underwent a remotely controlled mandibular positioner (RCMP) test during PSG monitoring. The ability of the RCMP test to eliminate OSA and the target protrusion at which that occurred was compared with the success of a custom oral MRA in the 33 subjects who completed the protocol. The RCMP test was a success in 15 subjects and a failure in 18 subjects. Appliance therapy was initiated in 38 subjects and completed in 33. MRA therapy was successful at target protrusion in 80% of subjects who had a successful RCMP test and failed in 78% of those who failed the RCMP test. In conclusion the remotely controlled mandibular positioner test outcome demonstrated a statistically significant association with mandibular repositioning appliance outcome. The target protrusion determined during the remotely controlled mandibular positioner test was the effective therapeutic protrusion in subjects with a successful remotely controlled mandibular positioner test.