TY - JOUR T1 - Tuberculosis, HIV seroprevalence and intravenous drug abuse in prisoners JF - European Respiratory Journal JO - Eur Respir J SP - 298 LP - 304 DO - 10.1183/09031936.05.00136004 VL - 26 IS - 2 AU - F. A. Drobniewski AU - Y. M. Balabanova AU - M. C. Ruddy AU - C. Graham AU - S. I. Kuznetzov AU - G. I. Gusarova AU - S. M. Zakharova AU - A. S. Melentyev AU - I. M. Fedorin Y1 - 2005/08/01 UR - http://erj.ersjournals.com/content/26/2/298.abstract N2 - High rates of tuberculosis (TB) and HIV are believed to exist in Russian prisons. Prisoners with TB were studied in order to identify the following: 1) prevalence of HIV, and risk factors for HIV and other blood-borne virus infections; and 2) clinical and social factors that might compromise TB treatment effectiveness and/or patient adherence and, hence, encourage treatment failure. A 1-yr cross-sectional prevalence study of 1,345 prisoners with TB was conducted at an in-patient TB facility in Samara, Russian Federation. HIV and hepatitis B and/or C co-infection occurred in 12.2% and 24.1% of prisoners, respectively, and rates were significantly higher than in civilians. Overall, 48.6% of prisoners used drugs, of which 88.3% were intravenous users. Prisoners were more likely to be intravenous drug users and HIV positive compared with civilians with TB, and 40.2% of prisoners shared needles. Two-thirds of prisoners (68.6%) had received previous TB drug therapy (frequently multiple, interrupted courses) and were significantly more likely than civilians to have had previous therapy consistent with the high drug-resistance rates seen. Prisons are major drivers of the tuberculosis and HIV epidemics. Novel strategies are needed to reduce the spread of blood borne diseases, particularly in intravenous drug users. ER -