TY - JOUR T1 - <em>Chlamydophila pneumoniae</em> in asthma JF - European Respiratory Journal JO - Eur Respir J SP - 392 LP - 392 DO - 10.1183/09031936.04.00131404 VL - 25 IS - 2 AU - D. L. Hahn Y1 - 2005/02/01 UR - http://erj.ersjournals.com/content/25/2/392.1.abstract N2 - To the Editors: Biscione et al. 1 reported a significant association of upper airway Chlamydophila pneumoniae RT-PCR positivity in atopic asthmatics (cumulative rate 22%) compared with nonatopic nonasthmatic spouses (9%). In the discussion, Biscione et al. 1 argued in favour of acute, rather than chronic, infection as the explanation for their observation that detection was mostly intermittent rather than persistent. I would like to address three issues raised by this interesting study. First, in the introduction, Biscione et al. 1 stated that C. pneumoniae serology could not differentiate acute from other infections. It is correct to state that serology cannot diagnose … ER -