TY - JOUR T1 - Amfepramone does not cause primary pulmonary hypertension JF - European Respiratory Journal JO - Eur Respir J SP - 790 LP - 790 DO - 10.1183/09031936.04.00119304 VL - 23 IS - 5 AU - G. Di Sacco Y1 - 2004/05/01 UR - http://erj.ersjournals.com/content/23/5/790.1.abstract N2 - To the Editor: The article by Abramowicz et al. 1 should show the first case of primary pulmonary hypertension (PPH) associated with the use of amfepramone (diethylpropion), an anorectic drug, and BMPR2 mutation. In my opinion, the relationship between amfepramone and the rise of PPH in this case is unproven. BMPR2 mutation is related to PPH without use of anorectics. Autosomal dominant germline mutations in BMPR2 have been identified in ∼55% … ER -