TY - JOUR T1 - Pulmonary infiltrates in Costello Syndrome JF - European Respiratory Journal JO - Eur Respir J SP - 783 LP - 785 DO - 10.1183/09031936.04.00073704 VL - 23 IS - 5 AU - N. Waldburg AU - F. Buehling AU - M. Evert AU - O. Burkhardt AU - T. Welte Y1 - 2004/05/01 UR - http://erj.ersjournals.com/content/23/5/783.abstract N2 - This paper reports on a patient with diffuse pulmonary infiltrates directly related to Costello Syndrome. This congenital disorder is characterised by multiple congenital abnormalities, such as psychomotor retardation, short stature, redundant skin, papillomata, curly hair, relative macroencephaly, distinctive face and various defects of internal organs. This study is the first to document the histopathological findings in the lungs. Most conspicuous was the depositing of abnormal collagen and elastic fibres and the development of endogenous lipid pneumonia. ER -