RT Journal Article SR Electronic T1 A randomised trial to evaluate the self-administered standardised chronic respiratory questionnaire JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 31 OP 40 DO 10.1183/09031936.04.00029704 VO 25 IS 1 A1 H. J. Schünemann A1 R. Goldstein A1 M. J. Mador A1 D. McKim A1 E. Stahl A1 M. Puhan A1 L. E. Griffith A1 B. Grant A1 P. Austin A1 R. Collins A1 G. H. Guyatt YR 2005 UL http://erj.ersjournals.com/content/25/1/31.abstract AB The original chronic respiratory questionnaire (CRQ), one of the most widely used measures of health-related quality of life (HRQL) in chronic respiratory disease (CRD), is traditionally interviewer administered (IA) and includes an individualised dyspnoea domain. The present authors studied the impact of self-administered (SA) and standardised dyspnoea questions on CRQ measurement properties. In a factorial design multicentre trial, 177 patients with CRD (mean age 67.7 yrs; mean forced expiratory volume in one second per cent predicted 44.6%) were randomised to CRQ-IA (n = 86) or CRQ-SA (n = 91), and to initially complete the standardised or individualised items before and after respiratory rehabilitation. While maintaining validity, the CRQ-SA proved more responsive to changes in HRQL than the CRQ-IA in all domains. Compared with the standardised dyspnoea domain, the individualised dyspnoea domain indicated greater responsiveness. The correlations of baseline scores and change scores with other HRQL instruments indicated good validity of the CRQ-SA. In conclusion, self-administration and standardisation of the chronic respiratory questionnaire maintains validity and responsiveness relative to the interviewer-administered chronic respiratory questionnaire. These results challenge the assumption that interviewer-administered questionnaires are superior to self-administered questionnaires in older patients with chronic respiratory disease.