RT Journal Article SR Electronic T1 Development of persistent late onset asthma following treatment with captopril JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 586 OP 588 DO 10.1183/09031936.93.02060586 VO 2 IS 6 A1 BJ Lipworth A1 JJ McMurray A1 RA Clark A1 AD Struthers YR 1989 UL http://erj.ersjournals.com/content/2/6/586.abstract AB We describe the first case of de novo asthma following treatment with the angiotensin converting enzyme (ACE) inhibitor captopril. Despite drug withdrawal there was evidence of persistent airways obstruction and bronchial hyperreactivity. This suggests the possibility that ACE inhibitors may uncover an asthmatic tendency in patients with pre-existing bronchial hyperreactivity.