PT - JOURNAL ARTICLE AU - BJ Lipworth AU - JJ McMurray AU - RA Clark AU - AD Struthers TI - Development of persistent late onset asthma following treatment with captopril AID - 10.1183/09031936.93.02060586 DP - 1989 Jun 01 TA - European Respiratory Journal PG - 586--588 VI - 2 IP - 6 4099 - http://erj.ersjournals.com/content/2/6/586.short 4100 - http://erj.ersjournals.com/content/2/6/586.full SO - Eur Respir J1989 Jun 01; 2 AB - We describe the first case of de novo asthma following treatment with the angiotensin converting enzyme (ACE) inhibitor captopril. Despite drug withdrawal there was evidence of persistent airways obstruction and bronchial hyperreactivity. This suggests the possibility that ACE inhibitors may uncover an asthmatic tendency in patients with pre-existing bronchial hyperreactivity.