PT  - JOURNAL ARTICLE
AU  - J Hormbrey
AU  - MS Jacobi
AU  - CP Patil
AU  - KB Saunders
TI  - CO2 response and pattern of breathing in patients with symptomatic hyperventilation, compared to asthmatic and normal subjects
AID  - 10.1183/09031936.93.01090846
DP  - 1988 Oct 01
TA  - European Respiratory Journal
PG  - 846--851
VI  - 1
IP  - 9
4099  - http://erj.ersjournals.com/content/1/9/846.short
4100  - http://erj.ersjournals.com/content/1/9/846.full
SO  - Eur Respir J1988 Oct 01; 1
AB  - We studied six patients with symptomatic hyperventilation, using new techniques to quantify baseline variability of respiratory variables, and to assess CO2 sensitivity around the control point using a stimulus not detectable by the subject. We compared them with six normal subjects and six patients with mild asthma. Symptomatic hyperventilators had normal mean ventilation and end-tidal carbon dioxide tension (PETCO2) at rest. Asthmatic subjects had higher ventilation and lower PETCO2. Symptomatic hyperventilators had a larger number of sighs and abnormally wide fluctuations in baseline for inspiratory time, expiratory time, and PETCO2. These could not be explained by an abnormal ventilatory response to a transient CO2 input; the transient response near the control point was undoubtedly normal.