TY - JOUR T1 - Assessment of diaphragm paralysis with oesophageal electromyography and unilateral magnetic phrenic nerve stimulation JF - European Respiratory Journal JO - Eur Respir J SP - 596 LP - 599 DO - 10.1034/j.1399-3003.2000.15.28.x VL - 15 IS - 3 AU - YM Luo AU - ML Harris AU - RA Lyall AU - A Watson AU - MI Polkey AU - J Moxham Y1 - 2000/03/01 UR - http://erj.ersjournals.com/content/15/3/596.abstract N2 - The purpose of this study was to establish a sensitive and reliable method of diagnosing diaphragm paralysis by recording the diaphragm compound muscle action potential (CMAP) using a multipair oesophageal electrode and unilateral magnetic phrenic nerve stimulation. An oesophageal electrode catheter was designed containing six coils (1 cm wide and 3 cm apart), creating an array of four sequential electrode pairs. The oesophageal catheter was taped at the nose with the proximal electrode pair 40 cm from the nares. Eight patients with unilateral (n=5) or bilateral (n=3) diaphragm paralysis were studied. Five to seven phrenic nerve stimulations were performed at 80% of maximum magnetic stimulator output and the CMAPs were recorded simultaneously from the four pairs of electrodes. In the five patients with unilateral diaphragm paralysis, the CMAP amplitudes and latencies were 1.16+/-0.29 mV and 7.6+/-1.5 ms for functioning sides. No diaphragm CMAP could be detected when stimulating nonfunctioning phrenic nerves. This study shows that diaphragm paralysis can be reliably diagnosed by unilateral magnetic stimulation combined with a multipaired oesophageal electrode. ER -