@article {Sampol1156, author = {G Sampol and X Munoz and MT Sagales and S Marti and A Roca and M Dolors de la Calzada and P Lloberes and F Morell}, title = {Long-term efficacy of dietary weight loss in sleep apnoea/hypopnoea syndrome}, volume = {12}, number = {5}, pages = {1156--1159}, year = {1998}, doi = {10.1183/09031936.98.12051156}, publisher = {European Respiratory Society}, abstract = {Weight loss is associated with clinical improvement in sleep apnoea/ hypopnoea syndrome (SAHS). The aim of this study was to ascertain whether the therapeutic efficacy of dietary weight loss is maintained in the long-term. From a total of 216 overweight SAHS patients treated by only a weight reduction programme, 24 cured by this method (apnoea/hypopnoea index (AHI) at diagnosis 443+/-27.8, after weight loss 3+/-3.1) were re-evaluated after a mean (+/-SD) period of 94.3+/-27.4 months post-cure. No correlation was found between changes in AHI and body mass index experienced by each patient in the two phases of the study (diagnosis to cure and cure to long-term follow-up), r=0.29, p=0.156, demonstrating a marked intra-individual variability. Six of the 13 patients who maintained their weight presented recurrence of SAHS (AHI 40.5+/-24.1) as did eight of the 11 who had regained weight (AHI 44.3+/-23.). Weight maintenance was more frequent among patients who had continued to attend periodic appointments, 10/11 versus 3/13 (p\<0.001). In conclusion, weight-loss efficacy is maintained in the long-term in some sleep apnoea/hypopnoea syndrome patients. This study indicates the need for periodic follow-up of these patients as a reinforcement for weight maintenance and for early detection of the reappearance of sleep apnoea/hypopnoea syndrome.}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/12/5/1156}, eprint = {https://erj.ersjournals.com/content/12/5/1156.full.pdf}, journal = {European Respiratory Journal} }