RT Journal Article
SR Electronic
T1 Alpha-fetoprotein producing pulmonary blastoma in a patient with systemic sclerosis: pathogenetic analysis
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 1185
OP 1187
DO 10.1183/09031936.98.11051185
VO 11
IS 5
A1 Kasuga, I
A1 Miyamoto, D
A1 Ichinose, Y
A1 Chimangul, W
A1 Minemura, K
A1 Utsumi, K
A1 Yonemaru, M
A1 Serizawa, H
A1 Ebihara, Y
A1 Toyama, K
YR 1998
UL http://erj.ersjournals.com/content/11/5/1185.abstract
AB We describe a rare case of pulmonary blastoma complicated with systemic sclerosis. The serum alpha-fetoprotein level was elevated at presentation and the biopsied tumour stained positively against anti-alpha-fetoprotein antibody. The alpha-fetoprotein produced autonomously by tumour cells was of yolk-sac origin. Although the pathogenesis of pulmonary blastoma has not been clarified, we suggest that this pulmonary blastoma is a type of yolk-sac tumour.