PT - JOURNAL ARTICLE AU - Kasuga, I AU - Miyamoto, D AU - Ichinose, Y AU - Chimangul, W AU - Minemura, K AU - Utsumi, K AU - Yonemaru, M AU - Serizawa, H AU - Ebihara, Y AU - Toyama, K TI - Alpha-fetoprotein producing pulmonary blastoma in a patient with systemic sclerosis: pathogenetic analysis AID - 10.1183/09031936.98.11051185 DP - 1998 May 01 TA - European Respiratory Journal PG - 1185--1187 VI - 11 IP - 5 4099 - http://erj.ersjournals.com/content/11/5/1185.short 4100 - http://erj.ersjournals.com/content/11/5/1185.full SO - Eur Respir J1998 May 01; 11 AB - We describe a rare case of pulmonary blastoma complicated with systemic sclerosis. The serum alpha-fetoprotein level was elevated at presentation and the biopsied tumour stained positively against anti-alpha-fetoprotein antibody. The alpha-fetoprotein produced autonomously by tumour cells was of yolk-sac origin. Although the pathogenesis of pulmonary blastoma has not been clarified, we suggest that this pulmonary blastoma is a type of yolk-sac tumour.