TY - JOUR T1 - Constrictive bronchiolitis obliterans and paraneoplastic pemphigus JF - European Respiratory Journal JO - Eur Respir J SP - 934 LP - 937 DO - 10.1034/j.1399-3003.1999.13d39.x VL - 13 IS - 4 AU - Y Hasegawa AU - K Shimokata AU - S Ichiyama AU - H Saito Y1 - 1999/04/01 UR - http://erj.ersjournals.com/content/13/4/934.abstract N2 - Constrictive bronchiolitis obliterans is rare, and the pathogenesis of the disease often remains unknown. This study reports on the case of a 38 yr-old female with constrictive bronchiolitis obliterans and paraneoplastic pemphigus associated with malignant lymphoma. The patient developed progressive obstructive lung disease. The chest radiograph showed almost normal lungs. Paraneoplastic pemphigus is a newly described syndrome in which patients have autoantibodies binding to some epithelia, including in the respiratory tract. The disease develops in association with non-Hodgkin's lymphomas or other malignant neoplasms. The case presented here suggests that constrictive bronchiolitis obliterans associated with paraneoplastic pemphigus may be one of the facets of autoimmune responses in this context. ER -