RT Journal Article SR Electronic T1 Quality of life and its determinants in asthma patients in the Fez-Meknes region, Morocco JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA2079 DO 10.1183/13993003.congress-2023.PA2079 VO 62 IS suppl 67 A1 Bahra, Nassiba A1 El Yaagoubi, Soukaina A1 Bourkhime, Hind A1 Tachfouti, Nabil A1 Berraho, Mohamed Amine A1 Serraj, Mounia A1 Benjelloun, Mohammed Chakib A1 Aamara, Bouchra A1 El Fakir, Samira YR 2023 UL https://publications.ersnet.org//content/62/suppl_67/PA2079.abstract AB Introduction: Asthma is a chronic airway disease that can significantly affect patients' quality of life.Objective: To measure quality of life and identify its determinants in patients with asthma.Methods: A cross-sectional study was conducted in 2021 among asthma patients in Fez University hospital. Data were collected using an anonymous face to face questionnaire including sociodemographic and clinical data. Moroccan version of the SF12 scale was used to measure quality of life.SF-12 outcomes included the 8 domains, physical component and mental component summary scores, and the Short-Form Six-Dimension health utility score. uni-variate analysis were performed to measure association between quality of life and other factors, using Student's t test.Results: We included 67 patients, 77.6% of whom were female, the mean age was 52.1±14.6 years and that of FEV1 (forced expiratory volume in seconds) 1.7±0.8ml, 77.3% were illiterate, 14.9% smokers, 15.0% diabetics, and 14.9% hypertensive, 82.1% had a stage 3 or 4 and 66.1 had controlled asthma.The mean physical quality of life was 36.9±13.0, and mental quality of life 35.9±19.4.Physical quality of life was more impaired in patients older than 50 years (m=32.9 vs. 43.3 (p=0.005)), illiterate (m=32.7vs 43.7 (p=0.022)), hypertensive (m=28.9 vs. 38.4 (p=0.032)) and patients with low FEV1 (r=0.29, p=0.02)Mental quality of life was more impaired in patients aged over 50 years (m=30.1vs 45.2 (p=0.002)), in diabetics (m= 24.0 vs. 38.1(p=0.034)) and in patients with low FEV1 (r=0.3, p=0.018).Conclusion: Our results show an altered quality of life in asthmatics, hence the interest to take into account this aspect in the management of these patients.FootnotesCite this article as: European Respiratory Journal 2023; 62: Suppl. 67, PA2079.This abstract was presented at the 2023 ERS International Congress, in session “Inflammatory endotyping: the macrophage across disease areas”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).