PT  - JOURNAL ARTICLE
AU  - Galdeano Lozano, Marina
AU  - Martin Pascual, Adriana
AU  - Fernandez Arias, Carmen
AU  - Morancho Pallaruelo, Ariadna Ning
AU  - Hernandez Guillamet, Guillem Hernandez Guillamet
AU  - López Seguí, Francesc
AU  - Hernández Biette, Agnes
AU  - Aldás Criado, Irene
AU  - Marin Muñiz, Antoni
AU  - Matute Villacis, Monica
AU  - Garcia Olivé, Ignasi
AU  - Abad Capa, Jorge
TI  - Analysis of the clinical characteristics and comorbidities of patients with COPD and home mechanical ventilation
AID  - 10.1183/13993003.congress-2023.PA526
DP  - 2023 Sep 09
TA  - European Respiratory Journal
PG  - PA526
VI  - 62
IP  - suppl 67
4099  - http://erj.ersjournals.com/content/62/suppl_67/PA526.short
4100  - http://erj.ersjournals.com/content/62/suppl_67/PA526.full
SO  - Eur Respir J2023 Sep 09; 62
AB  - Home Mechanical Ventilation (HMV) in patients with COPD and stable hypercapnia is postulated as a recommended treatment but with a low level of evidence. The objective of this study is to assess what clinical characteristics and comorbidities are related to HMV failure and the consequences in terms of economical cost.Observational study of COPD carriers of HMV was performed. We performed a logistic regression using STATA, taking into account comorbidities as dependent variables, and calculating the ODDs Ratio with their confidence intervals (IC). The number of admissions, emergencies and deaths, were obtained through SAP, calculating the associated costs. We included 68 patients, 73% men aged 71 years [55-86 years]. The phenotype was emphysema (60.3%) and the obstruction was 42.3% [15-117%]; the prevalent comorbidity was obstructive sleep apnea. The average pCO2 prior to the start of the HMV was 57 mmHg [38-81] and the average pCO2 after initiation 46 mmHg [36-68]. A significant improvement is objectified (decrease >20% pCO2) after the establishment of HMV. There were 61 admissions, 53 emergency room, 489 consultations and only 2 deaths. The patient with hospital admissions, made a healthcare expenditure of around 9.200 Eur. The expenditure of those who required the least admissions as 126 Eur. Reduction pCO2 compared to the onset of HMV in 51.5% of patients. No comorbidities associated with HMV. FootnotesCite this article as: European Respiratory Journal 2023; 62: Suppl. 67, PA526.This abstract was presented at the 2023 ERS International Congress, in session “Inflammatory endotyping: the macrophage across disease areas”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).