RT Journal Article SR Electronic T1 Activity levels and quality of life in long COVID patients JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 4259 DO 10.1183/13993003.congress-2022.4259 VO 60 IS suppl 66 A1 J Martín Núñez A1 A Calvache Mateo A1 A Rodríguez López A1 I Calles Plata A1 A Ortiz Rubio A1 I Torres Sánchez A1 M C Valenza YR 2022 UL http://erj.ersjournals.com/content/60/suppl_66/4259.abstract AB Introduction: Long COVID is a syndrome characterised by persistence of symptoms after acute SARS-CoV-2 infection. Patients with long COVID may present with a wide range of symptoms, including respiratory, cardiovascular, musculoskeletal, neurological, gastrointestinal and other symptoms. These symptoms can lead to a decrease in activity levels and health-related quality of life of patients.Objetive: The main objetive of this study was to evaluate the activity levels and health-related quality of life of long COVID patients one year after infection.Patients and methods: In this observational study, long COVID patients were included. These patients were evaluated one year after infection and they were compared to a control group of subjects who had successfully recovered from COVID infection without persistent symptoms matched by age and gender. The activity levels of the patients were assessed with the international physical activity questionnaire (IPAQ) and the health-related quality of life was assessed with the EuroQoL 5 dimensions 5 levels (EQ-5D-5L).Results: A total of 455 patients and 451 controls were included in this study. The IPAQ (p<0,001) and the five dimensions of EQ-5D-5L (p<0,001) showed significant results compared to the control group.Conclusion: This study found that long COVID syndrome patients presented poorer activity levels and health-related quality of life. The development of treatment programmes tailored to their needs will help to prevent the deterioration caused by this syndrome.FootnotesCite this article as Eur Respir J 2022; 60: Suppl. 66, 4259.This article was presented at the 2022 ERS International Congress, in session “-”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).