RT Journal Article SR Electronic T1 Hospitalizations in OSA patients JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 4248 DO 10.1183/13993003.congress-2022.4248 VO 60 IS suppl 66 A1 Cancela da Fonseca Ferreira Santos, G S A1 Van Zeller, M A1 Carriço, F A1 Rodrigues, D A1 Torres Redondo, M A1 Drummond, M YR 2022 UL https://publications.ersnet.org//content/60/suppl_66/4248.abstract AB Obstructive sleep apnea (OSA) is associated with cardiovascular comorbidities and other chronic diseases, accounting for long-term morbidity, with elevated symptomatic burden and hospitalizations. We aim to study the hospitalizations' causes in OSA patients and its relation to OSA severity and PAP therapy adhesion.This is a retrospective study including 281 hospitalizations corresponding to 200 OSA patients during 2019. Mean age 65 years, 67% were males, and 43,5% (n=87) had severe OSA; 85% patients under PAP; 60,4% (n=102) good adherent patients. Overlap with obesity hypoventilation syndrome (n=7) and COPD (n=48) was noticed. The main causes of hospitalization were heart failure (n=23), COPD (n=17), bariatric surgery (n=12) and stroke (n=11); mean length of stay was 8 days. About 1,5% (n=3) patients needed intensive care.The number of hospitalizations in severe OSA were statistically higher than in non-severe OSA (1,53 vs 1,27; p<0.05). Also hospital re-admissons were higher in severe OSA (p<0,05), such as 30-day re-admissions (64%). Hospital length stay was higher in readmitted patients (9,7 vs 6,8, p<0,05). OSA severity and PAP non-adherence is related with higher hospitalization’ length (p< 0,05). Co-morbidities were associated with higher number of hospitalizations in OSA (p>0.05, 1.55 vs 1.46).Hospitalizations are a real burden in severe OSA patients with an elevated rate of readmissions. The main causes of hospitalizations in OSA patients were congestive heart failure and COPD exacerbations conferring an additional symptomatic burden in these patients. OSA treatment should be early introduced as it seems to have a positively impact on the length of hospitalizations, especially noticed in severe OSA.FootnotesCite this article as Eur Respir J 2022; 60: Suppl. 66, 4248.This article was presented at the 2022 ERS International Congress, in session “-”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).