PT  - JOURNAL ARTICLE
AU  - A Papi
AU  - D P Roggeri
AU  - A Roggeri
TI  - Health economic implications of the use of erdosteine in patients with chronic obstructive lung disease
AID  - 10.1183/13993003.congress-2022.4493
DP  - 2022 Sep 04
TA  - European Respiratory Journal
PG  - 4493
VI  - 60
IP  - suppl 66
4099  - http://erj.ersjournals.com/content/60/suppl_66/4493.short
4100  - http://erj.ersjournals.com/content/60/suppl_66/4493.full
SO  - Eur Respir J2022 Sep 04; 60
AB  - Introduction: Erdosteine, a thiol- based drug, is effective in reducing exacerbation risk in chronic obstructive pulmonary disease (COPD) patients irrespective of concurrent treatment with ICS.1, 2Aims and objectives: Aim of this analysis was to evaluate the impact of the treatment with erdosteine on hospitalizations and related costs for COPD patients in Countries with an established use of the drug.Hospitalizations number and costs were estimated based on the difference in hospitalization rate due to COPD exacerbation between erdosteine-treated patients versus placebo-treated patients reported in RESTORE clinical study.1Hospitalization costs in charge to health services and COPD prevalence were collected for eleven Countries worldwide, where the drug is currently marketed.Erdosteine is not reimbursed in all considered Countries so, conservatively, drug cost was not included in the analysis.Results: Data related to the following Countries were analyzed: Italy, Turkey, Bulgaria, Poland, Czech Republic, Romania, UK, Greece, Finland, Singapore and Philippines.Considering COPD prevalence for the selected Countries, erdosteine could be associated with a reduction in the number of hospitalizations per Country/year up to about 88,000 corresponding to an annual saving up to €75 millions.Conclusions: The treatment with erdosteine can be considered as an option to contribute to the reduction in COPD related hospitalizations and costs in charge to NHS.References1)     Dal Negro RW et al Eur Respir J. 2017;50(4):17007112)     GOLD (Global Initiative for Chronic Obstructive Lung Disease) Report 2022FootnotesCite this article as Eur Respir J 2022; 60: Suppl. 66, 4493.This article was presented at the 2022 ERS International Congress, in session “-”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).