RT Journal Article
SR Electronic
T1 Climate change and COPD severity: a pilot study in Taiwan
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 1998
DO 10.1183/13993003.congress-2022.1998
VO 60
IS suppl 66
A1 H Chuang
A1 M T Huan
A1 T Chen
A1 Y Lu
A1 K Chen
A1 S Ho
A1 C Wu
A1 K Lee
YR 2022
UL http://erj.ersjournals.com/content/60/suppl_66/1998.abstract
AB Chronic Obstructive Pulmonary Disease (COPD) is an environmental lung disease and its disease stability is associated with seasonal variations. However, the impacts of climate change on COPD severity remain unclear. The objective of this study was to examine the association of climate change with COPD severity. A cross-sectional study in 117 COPD patients was conducted in a hospital in Taiwan. We measured the lung function, six-minute walk distance (6MWD), oxygen desaturation and white cell count and linked to lag 0-1, 0-3, and 0-5 year of individual-level exposure to relative humidity (RH) and temperature. We observed that 1% RH increase in lag 0-3 year and lag 0-5 year was associated with 4.2% and 3.7% increase in the FEV1, whereas 1oC temperature increase in lag 0-3 year and lag 0-5 year was associated with 3.9% and 4.5% decrease in the oxygen desaturation, respectively (P<0.05). We observed that 1% increase in the lag 0-1 year RH was associated with 0.3% increase in eosinophil and 1.7% increase in lymphocyte (P<0.05). In conclusion, we observed that climate change increased the risk of COPD severity. Climate change could be an important public health concern in terms of respiratory disease severity.FootnotesCite this article as Eur Respir J 2022; 60: Suppl. 66, 1998.This article was presented at the 2022 ERS International Congress, in session “-”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).