RT Journal Article
SR Electronic
T1 lung function decline in chronic kidney disease
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 4599
DO 10.1183/13993003.congress-2022.4599
VO 60
IS suppl 66
A1 C Y KIM
A1 Y N Kim
A1 B K Kim
YR 2022
UL http://erj.ersjournals.com/content/60/suppl_66/4599.abstract
AB Background: There is some evidence that lung function and chronic kidney disease (CKD) may be related. Previous studies reveals that lung function decline associates with increased CKD. On the contrary lung function decline in CKD patient has not been studied. We evaluated the impact of CKD and lung function decline in a large-scale longitudinal study.Method: A total of 100,30 subjects were taken from community-based cohort were recruited. longitudinal analyses were conducted among subjects who participated in community-based cohort during 14 years (between 2001 and 2014). follow up period. We investigated the Lung function decline during the follow-up period according to with and without CKD.Result: When compared subjects with and without ckd clinical variable that such as age, sex, BMI, and smoking status were different. After propensitity score matching using those variable, there was no difference in baseline clinical characteristics. we analyzed the association chronic kidney disease and the Lung function decline using linear mixed model(LMN) for association and interaction to time effect. LMN model shows the rapid decline of forced vital capacity (FVC) values than for CKD group compared with those without CKD group with time interaction(overall p value=0.0012).Conclusions: CKD was associated with rapid lung function decline in community based cohort.FootnotesCite this article as Eur Respir J 2022; 60: Suppl. 66, 4599.This article was presented at the 2022 ERS International Congress, in session “-”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).