PT  - JOURNAL ARTICLE
AU  - S E O'Donnell
AU  - G Croce
AU  - F Mandurino Mirizzi
AU  - E Franceschi
AU  - W Karimeh
AU  - F Giuliani
AU  - D Radovanovic
AU  - P Santus
TI  - Pain, fatigue and psychological sequelae in patients surviving COVID-19: results from a prospective observational controlled study
AID  - 10.1183/13993003.congress-2022.4227
DP  - 2022 Sep 04
TA  - European Respiratory Journal
PG  - 4227
VI  - 60
IP  - suppl 66
4099  - http://erj.ersjournals.com/content/60/suppl_66/4227.short
4100  - http://erj.ersjournals.com/content/60/suppl_66/4227.full
SO  - Eur Respir J2022 Sep 04; 60
AB  - Background: Since the beginning of the COVID-19 pandemic, there has been a growing recognition of its psychiatric implications. Anxiety, stress and sleep disorders are the main issues faced by healthcare professionals but less is known on the general population. We sought to determine the prevalence of neuro-psychiatric disorders, pain and fatigue in COVID-19 patients compared to healthy controls. The secondary outcome was to define the determinants of such disorders.Methods: This single centre, prospective, observational, cohort study enrolled adult patients referring to the post-COVID-19 outpatient clinic of our University hospital from January 2021 to June 2021. Anthropometrical and functional respiratory data were collected, pain and fatigue were evaluated through a VAS scale while stress, anxiety, quality of sleep and the impact of the event were evaluated through questionnaires: perceived stress scale, ZUNG 1971, Pittsburgh and impact of events scale.Results: 301 cases and 115 controls were enrolled. The COVID-19 group had a higher prevalence of stress (scale points 18 vs 3, p<0.01), anxiety (ZUNG score 39 vs 21, p<0.01), and poor sleep (68.1% vs 6.1%, p<0.01). Alongside they had a significantly higher VAS pain score (2 vs 0, p<0.001) and VAS fatigue (3 vs 0, p<0.001). Female gender was the only feature that could predict fatigue, pain, anxiety, poor sleep quality and post-traumatic stress disorder syndrome. COVID-19 severity wasn't associated with any psichological sequelae.Conclusions: In an outpatient setting, stress, anxiety, sleep quality, pain and fatigue should be assessed in the holistic view of post-COVID-19 patients, especially in femalesFootnotesCite this article as Eur Respir J 2022; 60: Suppl. 66, 4227.This article was presented at the 2022 ERS International Congress, in session “-”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).