PT  - JOURNAL ARTICLE
AU  - Majek, P
AU  - Jankowski, M
AU  - Zejda, J E
AU  - Brożek, G
TI  - Heated Tobacco Products – are they safe alternative for traditional cigarettes?
AID  - 10.1183/13993003.congress-2022.4184
DP  - 2022 Sep 04
TA  - European Respiratory Journal
PG  - 4184
VI  - 60
IP  - suppl 66
4099  - http://erj.ersjournals.com/content/60/suppl_66/4184.short
4100  - http://erj.ersjournals.com/content/60/suppl_66/4184.full
SO  - Eur Respir J2022 Sep 04; 60
AB  - Heated Tobacco Products (HTPs), unlike traditional cigarettes, work by heating the tobacco instead of burning it.The aim of the study was to assess the acute health effects of short-term use of Heated Tobacco Products.The study protocol included 120 healthy people, with median age 24 [22;26] years, divided into 3 groups, equal by gender, according to their smoking status: 40 non-smokers (C), 40 traditional tobacco smokers (T) and 40 HTP users (H). Heart rate (HR), blood pressure (SBP/DBP), saturation, exhaled CO, exhaled NO, airway temperature and spirometry were measured before and right after use of HTP / cigarette or after a smoking simulation in case of the C-group.Both, HTPs and cigarettes cause significant increase in SBP, DBP and HR (p<0.05), opposite to the C-group, where mentioned parameters decreased (p<0.05). Exhaled FeNO decline was observed in the H group (13.1±5.9 to 11.4±5.4; p<0.05) and the T group (10.3±5.8 to 9.5±6.4, p=0.02). Exhaled CO increased significantly after the exposure to cigarettes and heated tobacco (from 6 [4;10] to 11 [8;15], p<0.05; from 4 [3;5] to 4[3;5,5], p=0.01, respectively) and the difference was significantly greater in the T group. There were no statistically significant changes in saturation, airway temperature and spirometry parameters in all three groups (p>0.05). The C-group did not differ in exhaled NO and CO before and after the smoking simulation (p=0.07; p=0.4).Heated Tobacco Products affect in acute effects on respiratory and cardiovascular system, as well as traditional cigarettes.FootnotesCite this article as Eur Respir J 2022; 60: Suppl. 66, 4184.This article was presented at the 2022 ERS International Congress, in session “-”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).