RT Journal Article
SR Electronic
T1 Cognitive impairment as a sequel to SARS-CoV-2 infection
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 4245
DO 10.1183/13993003.congress-2022.4245
VO 60
IS suppl 66
A1 A Rosas Trujillo
A1 F Casarín López
A1 V Baltazar Chávez
A1 V Peláez Hernández
A1 A Orea Tejeda
A1 C D Ledesma Ruíz
A1 G L Luna Rodríguez
A1 N Camácho Mendoza
YR 2022
UL http://erj.ersjournals.com/content/60/suppl_66/4245.abstract
AB Introduction: COVID-19 survivor patients report a complaint subjectively related to memory and attention-concentration problems when carry out their daily activities.Objective: To investigate the presence of cognitive sequelae associated with COVID-19.Method: An observational cross-sectional study was conducted. Participated 229 COVID-19 survivor patients, who were evaluated with Montreal Cognitive Assessment (MoCA) and classified into three groups: a) severe cognitive impairment (G1, <13points, n=11), b) mild cognitive impairment (G2, 13-21 points, n=34), and c) without cognitive alterations (G3, 22-30 points, n=184). Statistical analyses were performed in SPSS V25.Results: Average age and male sex: G1: 67.36±10.71, 63.6%; G2: 58.76±11.55, 61.8%; G3: 53.32±11.39, 58.7%. G1 presented statistically differences (p <0.001) in all cognitive functions with the other groups (G1, G2, G3): visuospatial/executive ability (0.09±0.30, 0.53±0.50, 0.83±0.38), identification (2.00±0.89, 2.82±0.38, 2.92±0.32), attention (2.45±0.82, 3.97±1.16, 5.02±0.97), repetition (0.18±0.40, 0.29±0.46, 1.02±0.79), fluency (0.18±0.40, 0.68±0.47, 0.93±0.24), abstraction (0.18±0.40, 0.68±0.72, 1.41±0.77), deferred remembering (0.73±1.10, 1.44±1.37, 3.13±1.36) and orientation (4.64±0.92, 5.35±0.73, 5.79±0.49); except in executive ability, identification, repetition, abstraction and deferred remembering with respect to G2 (p<0.05).Conclusions: Cognitive alterations were found in patients post- COVID, especially in attention and deferred remembering, which could be related to errors of execution in other areas. In the case of the severe cognitive impairment, age may be a related variable. Necessary integrate this variable in the rehabilitation plan for a better prognosis and quality of life of patients.FootnotesCite this article as Eur Respir J 2022; 60: Suppl. 66, 4245.This article was presented at the 2022 ERS International Congress, in session “-”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).