TY - JOUR T1 - Predictors of anxiety depression disorders during active pulmonary tuberculosis JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2022.3185 VL - 60 IS - suppl 66 SP - 3185 AU - I Nouira AU - A Ben Mansour AU - M L Sidi Oumar AU - H Daghfous AU - S Ben Saad AU - F Tritar Y1 - 2022/09/04 UR - http://erj.ersjournals.com/content/60/suppl_66/3185.abstract N2 - Introduction: Tuberculosis is a global public health problem. It affects the quality of life with a significant psychological impact. The aim of this study is to determine the prevalence and predictors of anxiety and depression in patients with active tuberculosis.Methods: A prospective study using a predefined Hospital Anxiety and Depression Scale (HAD) questionnaire conducted in pneumology “C”department of Mami Ariana Tunisia hospital, between January 2020 and February 2022. Two groups were compared: G1 (normal or borderline mood, n=45) and G2 (anxious or depressed, n=48). Patients with a psychiatric history were not included.Results: One hundred and fifty patients were questioned. Ninety-three answered (62%). Mean age was 44 years. The sex ratio was1.38. Fourty eight (51.6%) patients had an anxiety-depressive syndrome. The mean HAD score was 12 [3-28]. Smoking intoxication was more frequent and greater in G2: [65% of smokers in G2 versus 34% in G1; p: 0.04]. Comorbidities such as diabetes and high blood pressure were more noted in G2. Acute respiratory failure was greater in patients in group G2. We found a statistically significant relationship between the extent of tuberculosis lesions, delay in sputum negativation and the severity of the anxiety-depressive syndrome (p: 0.002).Conclusion: The prevalence of anxiety and depression is quite high in patients with tuberculosis, especially in severe forms. Screening for these disorders is essential to improve patient care.FootnotesCite this article as Eur Respir J 2022; 60: Suppl. 66, 3185.This article was presented at the 2022 ERS International Congress, in session “-”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -