RT Journal Article
SR Electronic
T1 Home noninvasive ventilation in Myasthenia Gravis: features and predictors.
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 3776
DO 10.1183/13993003.congress-2022.3776
VO 60
IS suppl 66
A1 Quezada Reynoso, A
A1 Ferrer Espinosa, S
A1 Sancho Chinesta, J
A1 Giménez Samblás, E
A1 Ferrer Martí, A M
A1 Signes-Costa, J
YR 2022
UL https://publications.ersnet.org//content/60/suppl_66/3776.abstract
AB Noninvasive ventilation (NIV) has an important role during myasthenic crisis avoiding endotracheal intubation, however, there is few documented information concerning long-term home NIV in stable outpatients with myasthenia gravis (MG).The aim of the study was to describe the characteristics of a cohort with MG outpatients and to analyze contributing factors that could predict the need of NIV. We performed a cross-sectional study that included patients with diagnosis of MG managed in the Respiratory Care Unit in the previous year. Subjects underwent a clinical analysis that included demographics, functional respiratory evaluation (FRE), arterial blood gas analysis (ABG).37 were included (54,1% female). Blood test analysis showed 28 (75,7%) positive for AchRS antibodies. 29,7% patients were treated with home NIV. 70,3% had a diagnosis of generalized MG. Bulbar symptoms were developed in 13 (35,1%). Levels of PaCO2 and HCO3 in patients with MG improved after the initiation of NIV (Table 2). The only variable which predicted the need for long-term NIV in outpatients was predicted forced vital capacity (%FVC) (OR=0.94 95%CI 0.895–0.994, p=0.028).FVC is the only parameter that could predict the need of NIV.View this table:FootnotesCite this article as Eur Respir J 2022; 60: Suppl. 66, 3776.This article was presented at the 2022 ERS International Congress, in session “-”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).