PT - JOURNAL ARTICLE AU - Patil, Rajashri AU - Kuah, Jiaying AU - Brozik, Ian AU - Das, Indrajeet TI - Chest CT findings in 1st peak of COVID-19 pandemic in a U.K. tertiary centre AID - 10.1183/13993003.congress-2021.PA3245 DP - 2021 Sep 05 TA - European Respiratory Journal PG - PA3245 VI - 58 IP - suppl 65 4099 - http://erj.ersjournals.com/content/58/suppl_65/PA3245.short 4100 - http://erj.ersjournals.com/content/58/suppl_65/PA3245.full SO - Eur Respir J2021 Sep 05; 58 AB - Chest CT findings in 1st peak of COVID-19 pandemic in a U.K. tertiary centre.Objectives: To assess CT findings of confirmed SARSCoV and mortality during the 1st peak.Methods: Data on patient demographics and mortality was collected for inpatients who had CT chest with suspected COVID-19 between mid-March to end of April in University hospitals of Leicester. COVID-19 diagnosis was confirmed on positive SARSCoV RT-PCR test. CT severity score was based on British Society of Thoracic Imaging classification (% of lung involvement);1- Mild (<25%), 2-Mild-Moderate (25 to 50%) 3-Moderate-Severe (50% -75%), 4-Severe (>75%).Findings: 326 chest CT scans were done during the 6-week period with suspected COVID-19 infection, out of which 116(35.6%) were confirmed of COVID-19 on RT-PCR, 35(30%) of these patients died. Findings are given in the table; 11(9%) had atypical CT findings for COVID-19.Measurements and Main Results: COVID-19 positive patients with CT scans demonstrated increased mortality in elderly, non-white group and in those with severe CT scoring. Thromboembolic process has been considered as one of the pathophysiological process in COVID related mortality, however PE (Pulmonary embolism) on CT was not associated with mortality and presence of pleural effusion was associated with mortality and this needs further studies to explore. All RT-PCR positive (116)Died (35)Age <70 : ≥7079(68%):39(32%)21 (60%):14(40%)Gender M :F77(66%):39(34%)20 (57%):15(43%)Ethnicity White: Non-white72( 62%):44(38%)17(49%):18(51%)CT severity 1, 2,3,419 (16%):32 (27%):24 (21%): 30 (26%)4(11%):6(17%):5 (14%):17 (49%)PE17 (15%)6 (17 %) (p=0.32)Pleural Effusion19 (16%)14 (73%) (p<0.0001)FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3245.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).