RT Journal Article
SR Electronic
T1 Differences in inflammation biomarkers among COVID-19 and Non-COVID-19 pneumonia
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP PA659
DO 10.1183/13993003.congress-2021.PA659
VO 58
IS suppl 65
A1 ALEJANDRO REZOLA CARASUSAN
A1 Leyre Serrano Fernandez
A1 Luis Alberto Ruiz Iturriaga
A1 Edurne Echevarria Guerrero
A1 Beatriz Gonzalez Quero
A1 Joseba Andia Iturrate
A1 Elena Garay Llorente
A1 Jone Solorzano Santobeña
A1 Imanol Gonzalez Muñoz
A1 Rafael Zalacain Jorge
YR 2021
UL http://erj.ersjournals.com/content/58/suppl_65/PA659.abstract
AB Objective: Analyze differences in inflammatory parameters and evaluate their impact on the clinical course in COVID-19 and Non-COVID-19 community-acquired pneumonia (CAP).Methods: Prospective observational study including all patients hospitalized for Non-COVID-19 CAP in 2020 and COVID-19 in march-may 2020. We measured serum inflammatory markers at hospital admission and clinical course. Poor outcome: in-hospital mortality and/or need for high-flow oxygen therapy and/or invasive mechanical ventilation.Results: We analyzed 387 patients (308 COVID-19, 79 Non-COVID-19). Etiology was identified in 34.1% of Non- COVID-19 CAP. Figure 1: demographic characteristics, inflammatory markers and in-hospital course. Patients with COVID-19 had worse clinical course and major short-term mortality (11% vs 2.5%, p=0.002). Figure 2: inflammatory parameters in patients with poor outcome. Conclusions: Non-COVID-19 CAP had higher CRP and D-dimer whereas LDH level and lymphopenia were higher in COVID-19 patients. Demographic characteristics and comorbidities of both groups were similar; however, COVID-19 pneumonias had worse outcome and higher in-hospital mortality.FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA659.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).