RT Journal Article SR Electronic T1 Predictors and prognostic factors in a large Pulmonary embolism series JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA503 DO 10.1183/13993003.congress-2021.PA503 VO 58 IS suppl 65 A1 Shona Arlin Christopher A1 Richa Gupta A1 Barney Isaac A1 Devasahayam J Christopher YR 2021 UL http://erj.ersjournals.com/content/58/suppl_65/PA503.abstract AB Introduction: There are several risk factors associated with the development of pulmonary embolism(PE) and prognostic factors associated with mortality.Methods: In this prospective observational study, 222 pulmonary embolism suspects were screened for PE. Demographic details, clinical findings, predisposing factors were noted. CT-pulmonary angiogram was done to confirm PE. These variables were compared between those who were diagnosed to have PE and those without.Results: Malignancy was significantly higher in the PE group (P=0.003) and the non-PE group had significantly higher cardiovascular disease (P=0.009), chronic lung disease (P<0.001) and chronic liver disease (P=0.023). Univariate regression for prolonged hospitalization showed significant correlations with chronic heart disease (P=0.13;IRR=1.59) and chronic kidney disease (P=0.05;IRR=2.72) and negative correlation for malignancy (P = 0.026;IRR=0.64) and thrombolysis treatment (P=0.005;IRR= 0.57). Univariate regression for mortality at 3 months showed significant correlations with chronic pulmonary disease (P=0.013;IRR=3.03).Conclusion: Our largest Indian single centre study showed malignancy was risk factor for PE, whereas cardiovascular disease, chronic lung and chronic liver diseases were associated with Non - PE diagnosis. Prolonged hospital stay was associated with chronic heart disease and chronic kidney disease and mortality at 3 months with chronic pulmonary disease.FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA503.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).