TY - JOUR T1 - Health-psychologic features and health-related quality of life in persons with severe asthma JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2021.PA1802 VL - 58 IS - suppl 65 SP - PA1802 AU - Lina Rönnebjerg AU - Malin Axelsson AU - Hannu Kankaanranta AU - Bo Lundbäck AU - Linda Ekerljung Y1 - 2021/09/05 UR - http://erj.ersjournals.com/content/58/suppl_65/PA1802.abstract N2 - Introduction: Little is known about health-psychologic features and health-related quality of life (HRQoL) in persons with severe asthma. Hence, the aim was to explore these features among persons with severe asthma.Methods: In the population-based West Sweden Asthma Study, 68 persons with severe asthma completed questionnaires on HRQoL (SF-8), asthma control (ACT), general self-efficacy (GSE), beliefs about medications (BMQ), anxiety and depression (HADS). Severe asthma was based on GINA treatment steps 4/5. Sub-groups were compared with the Mann-Whitney U test and associations were explored using the Spearman’s r.Results: Women with severe asthma reported worse mental HRQoL and indicated more symptoms of anxiety on HADS compared to men with severe asthma. Persons with severe asthma and ACT<20 reported worse physical HRQoL and perceived their medication as more necessary than those with severe asthma and ACT≥20. Among persons with severe asthma, physical HRQoL was associated with ACT-score (r=.613, p>.001). Mental HRQoL was associated with symptoms of anxiety (r=-.670, p>.001), depression (r=-.499, p>.001), self-efficacy (r=.344, p=.004) and concerns of asthma medication side effects (r=-.340, p=.006) within the same group.Conclusions: Health-psychologic features and HRQoL were different between sub groups of severe asthma. Use of questionnaires in asthma management in healthcare might be helpful to identify these sub-groups and provide improved and preventive care.FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA1802.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -