RT Journal Article
SR Electronic
T1 Long-term air pollution exposure, greenness and health-related quality of life (HRQOL) in ECRHS
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP OA100
DO 10.1183/13993003.congress-2021.OA100
VO 58
IS suppl 65
A1 Siroux, Valerie
A1 Boudier, Anne
A1 Markevych, Iana
A1 Jacquemin, Bénédicte
A1 Abramson, Michael J
A1 Accordini, Simone
A1 Forsberg, Bertil
A1 Fuertes, Elaine
A1 Garcia-Aymerich, Judith
A1 Heinrich, Joachim
A1 Johanessen, Ane
A1 Leynaert, Bénédicte
A1 Pin, Isabelle
YR 2021
UL https://publications.ersnet.org//content/58/suppl_65/OA100.abstract
AB Introduction: Association studies of long-term air pollution exposure and greenness with HRQOL are rare and none account for asthma-rhinitis status.Aims: To study the cross-sectional associations of long-term air pollution exposure and greenness with HRQOL and the modification effect of asthma-rhinitis status on these associations.Methods: Participants to the second (n=6542) and third (n=3686) phase of the European Community Respiratory Health Survey (ECRHS), with data on SF-36 Physical and Mental Component Summary (PCS, MCS), annual mean residential air pollution exposures (NO2, PM2.5 and PM10) and greenness (Normalized Difference Vegetation Index (NDVI) in a 300m buffer) were included. For each exposure variable, we fitted mixed linear models for PCS and MCS, accounted for centre effect and repeated data, and adjusted for age, gender, BMI, smoking, occupation, and chronic diseases. Interaction terms between exposures and asthma and/or rhinitis status were further added.Results: 48% were men and the mean(SD) age of the ECRHSII and III participants were 43(7) and 54(7) years. Mean(SD) PCS and MCS were 49(10) and 50(11) at ECRHSII, and 47(11) and 51(10) at ECRHSIII. MCS was inversely associated with NO2, PM2.5 and PM10, and positively associated with NDVI (regression coefficients (95%CI) for one IQR change in exposure were -0.70 (-1.17; -0.23), -1.84 (-2.83; -0.85), -1.80 (-2.89; -0.71) and 0.91 (0.34; 1.48), respectively). No association was found for PCS. Similar association patterns were observed for each asthma-rhinitis phenotype.Conclusion: Higher long-term air pollution exposure and lower greenness were associated with higher MCS but not PCS, regardless of asthma-rhinitis status.FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, OA100.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).